Strontium (as Citrate) is a mineral with similar properties as calcium. It is unique in that it increases bone formation while also preventing bone resorption. 1,2,3
Mechanisms include:
- Increases pre-osteoblast replication and maturation into osteoblasts
- Incorporates into bone matrix increasing strength
- Inhibits osteoclast formation
- Inhibits resorption by osteoclasts
1. Dahl, S. G., Allain, P. et al. Incorporation and distribution of strontium in bone. Bone. 2001; 28(4):446-453.
2. Marie, P. J., Ammann, P. et al. Mechanisms of action and therapeutic potential of strontium in bone. Calcif Tissue Int. 2001; 69(3):121-129.
3. Marie, P. J. Optimizing bone metabolism in osteoporosis: insight into the pharmacologic profile of strontium ranelate. Osteoporos Int. 2003; 14 Suppl 3:S9-12.
If you are pregnant or nursing, consult your physician before taking this product.